NFL Odds: Lines and Spread for each of Sunday’s Week 11 Games

We’re officially at Week 11 of the 2021 NFL season as a bundle of games are scheduled for this weekend. There are a tone of exciting matchups going down this Sunday, November 21, which means that there’s a lot to keep track of. Fortunately, this betting guide has all of the lines and spreads for each of Sunday’s games in one place, making it easy to know everything that’s important for this week’s matchups.

Here’s a look at the odds heading into each of this Sunday’s Week 11 matchups, with odds courtesy of BetOnline.

NFL Odds: Detroit Lions vs Cleveland Browns

Odds via BetOnline as of Thursday, November 18

  • Record: Detroit Lions (0-8-1) vs Cleveland Browns (5-5)
  • Start time: 1 p.m. EST
  • Moneyline: Lions (+405) vs Browns (-510)
  • Spread: Lions +11.0 (-110) vs Browns -11.0 (-110)
  • Total: 43.0 — Over (-110), Under (-110)
  • Head-to-Head: Lions are 4-1 against the Browns in their last five games.

San Francisco 49ers vs Jacksonville Jaguars Odds

Odds via BetOnline as of Thursday, November 18

  • Record: San Francisco 49ers (4-5) vs Jacksonville Jaguars (2-7)
  • Start time: 1 p.m. EST
  • Moneyline: 49ers (-265) vs Jaguars (+225)
  • Spread: 49ers -6.0 (-112) vs Jaguars +6.0 (-108)
  • Total: 45.5 — Over (-106), Under (-114)
  • Head-to-Head: 49ers are 3-2 against the Jaguars in their last five games.

Indianapolis Colts vs Buffalo Bills Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Indianapolis Colts (5-5) vs Buffalo Bills (6-3)
  • Start time: 1 p.m. EST
  • Moneyline: Colts (+270) vs Bills (-325)
  • Spread: Colts +7.0 (-108) vs Bills -7.0 (-112)
  • Total: 50.0 — Over (-110), Under (-110)
  • Head-to-Head: Colts are 6-4 against the Bills in their last 10 games.

NFL Odds: Miami Dolphins vs New York Jets

Odds via BetOnline as of Thursday, November 18

  • Record: Miami Dolphins (3-7) vs New York Jets (2-7)
  • Start time: 1 p.m. EST
  • Moneyline: Dolphins (-177) vs Jets (+157)
  • Spread: Dolphins -3.0 (-125) vs Jets +3.0 (+105)
  • Total: 44.5 — Over (-110), Under (-110)
  • Head-to-Head: Dolphins are 8-2 against the Jets in their last 10 games.

Washington Football Team vs Carolina Panthers Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Washington Football Team (3-6) vs Carolina Panthers (5-5)
  • Start time: 1 p.m. EST
  • Moneyline: Washington (+146) vs Panthers (-166)
  • Spread: Washington +3.5 (-120) vs Panthers -3.5 (+100)
  • Total: 43.0 — Over (-108), Under (-112)
  • Head-to-Head: Panthers are 7-3 against Washington in their last 10 games.

Baltimore Ravens vs Chicago Bears Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Baltimore Ravens (6-3) vs Chicago Bears (3-6)
  • Start time: 1 p.m. EST
  • Moneyline: Ravens (-225) vs Bears (+195)
  • Spread: Ravens -4.5 (-110) vs Bears +4.5 (-110)
  • Total: 45.0 — Over (-116), Under (-104)
  • Head-to-Head: Bears are 4-2 against the Ravens in their last six games.

NFL Odds: New Orleans Saints vs Philadelphia Eagles

Odds via BetOnline as of Thursday, November 18

  • Record: New Orleans Saints (5-4) vs Philadelphia Eagles (4-6)
  • Start time: 1 p.m. EST
  • Moneyline: Saints (+116) vs Eagles (-136)
  • Spread: Saints +1.5 (+100) vs Eagles -1.5 (-120)
  • Total: 43.0 — Over (-110), Under (-110)
  • Head-to-Head: Saints are 7-3 against the Eagles in their last 10 games.

Houston Texans vs Tennessee Titans Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Houston Texans (1-8) vs Tennessee Titans (8-2)
  • Start time: 1 p.m. EST
  • Moneyline: Texans (+360) vs Titans (-450)
  • Spread: Texans +10.0 (-110) vs Titans -10.0 (-110)
  • Total: 44.5 — Over (-110), Under (-110)
  • Head-to-Head: Titans are 6-4 against the Texans in their last 10 games.

Green Bay Packers vs Minnesota Vikings Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Green Bay Packers (8-2) vs Minnesota Vikings (4-5)
  • Start time: 1 p.m. EST
  • Moneyline: Packers (-127) vs Vikings (+107)
  • Spread: Packers -1.0 (-125) vs Vikings +1.0 (+105)
  • Total: 49.0 — Over (-108), Under (-112)
  • Head-to-Head: Vikings are 5-4-1 against the Packers in their last 10 games.

NFL Odds: Cincinnati Bengals vs Las Vegas Raiders

Odds via BetOnline as of Thursday, November 18

  • Record: Cincinnati Bengals (5-4) vs Las Vegas Raiders (5-4)
  • Start time: 4:05 p.m. EST
  • Moneyline: Bengals (N/A) vs Raiders (N/A)
  • Spread: Bengals [Pick ‘Em] (-115) vs Raiders [Pick ‘Em] (-105)
  • Total: 49.5 — Over (-110), Under (-110)
  • Head-to-Head: Raiders are 5-4 against the Bengals in their last nine games.

Arizona Cardinals vs Seattle Seahawks Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Arizona Cardinals (8-2) vs Seattle Seahawks (3-6)
  • Start time: 4:25 p.m. EST
  • Moneyline: Cardinals (N/A) vs Seahawks (N/A)
  • Spread: Cardinals [Pick ‘Em] (-125) vs Seahawks [Pick ‘Em] (+105)
  • Total: 48.0 — Over (-110), Under (-110)
  • Head-to-Head: Seahawks are 5-4-1 against the Cardinals in their last 10 games.

Arizona Cardinals vs Seattle Seahawks Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Arizona Cardinals (8-2) vs Seattle Seahawks (3-6)
  • Start time: 4:25 p.m. EST
  • Moneyline: Cardinals (N/A) vs Seahawks (N/A)
  • Spread: Cardinals [Pick ‘Em] (-125) vs Seahawks [Pick ‘Em] (+105)
  • Total: 48.0 — Over (-110), Under (-110)
  • Head-to-Head: Seahawks are 5-4-1 against the Cardinals in their last 10 games.

Dallas Cowboys vs Kansas City Chiefs Odds

Odds via BetOnline as of Thursday, November 18

  • Record: Dallas Cowboys (7-2) vs Kansas City Chiefs (6-4)
  • Start time: 4:25 p.m. EST
  • Moneyline: Cowboys (+120) vs Chiefs (-140)
  • Spread: Cowboys +2.5 (-105) vs Chiefs -2.5 (-115)
  • Total: 56.0 — Over (-115), Under (-105)
  • Head-to-Head: Cowboys are 4-2 against the Chiefs in their last six games.

NFL Sunday Night Football Odds: Pittsburgh Steelers vs Los Angeles Chargers

Odds via BetOnline as of Thursday, November 18

  • Record: Pittsburgh Steelers (5-3-1) vs Los Angeles Chargers (5-4)
  • Start time: 8:20 p.m. EST
  • Moneyline: Steelers (N/A) vs Chargers (N/A)
  • Spread: Steelers +5.5 (-101) vs Chargers -5.5 (-119)
  • Total: 47.0 — Over (-110), Under (-110)
  • Head-to-Head: Steelers are 7-3 against the Chargers in their last 10 games.

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Devon Platana
After graduating with a Masters degree in Journalism, Devon joined USGS to improve his sports writing skills. As a lifelong sports fan, one of Devon’s favorite things to do is analyze statistics across all sports.