We are officially more than one week into the 2021 NFL season as a bundle of games are scheduled for this weekend. There are a ton of big matchups scheduled for Sunday, September 19, which means that there’s a lot to keep track of. Fortunately, this betting guide has all of the lines and spreads for each of Sunday’s games in one place, making it easy to know everything that’s important.
Here’s a look at the odds heading into each of this Sunday’s Week 2 matchups, with odds courtesy of Bovada.
NFL Odds: Buffalo Bills vs Miami Dolphins
Odds via Bovada as of Friday, September 17
- Record: Buffalo Bills (0-1) vs Miami Dolphins (1-0)
- Start time: 1 p.m. EST
- Moneyline: Bills (-180) vs Dolphins (+155)
- Spread: Bills -3.5 (-105) vs Dolphins +3.5 (-115)
- Total: 47.5 — Over (-110), Under (-110)
- Head-to-Head: Bills are 7-3 against the Dolphins in their last 10 games.
Cincinnati Bengals vs Chicago Bears
Odds via Bovada as of Friday, September 17
- Record: Cincinnati Bengals (1-0) vs Chicago Bears (0-1)
- Start time: 1 p.m. EST
- Moneyline: Bengals (+110) vs Bears (-130)
- Spread: Bengals +2.0 (-110) vs Bears -2.0 (-110)
- Total: 45.0 — Over (-110), Under (-110)
- Head-to-Head: Bengals are 3-3 against the Bears in their last six games.
Denver Broncos vs Jacksonville Jaguars
Odds via Bovada as of Friday, September 17
- Record: Denver Broncos (1-0) vs Jacksonville Jaguars (0-1)
- Start time: 1 p.m. EST
- Moneyline: Broncos (-270) vs Jaguars (+220)
- Spread: Broncos -6.0 (-115) vs Jaguars +6.0 (-105)
- Total: 45.0 — Over (-110), Under (-110)
- Head-to-Head: Jaguars are 6-4 against the Broncos in their last 10 games.
NFL Odds: Houston Texans vs Cleveland Browns
Odds via Bovada as of Friday, September 17
- Record: Houston Texans (0-1) vs Cleveland Browns (0-1)
- Start time: 1 p.m. EST
- Moneyline: Texans (+475) vs Browns (-700)
- Spread: Texans +13.0 (-110) vs Browns -13.0 (-110)
- Total: 48.0 — Over (-110), Under (-110)
- Head-to-Head: Texans are 7-3 against the Browns in their last 10 games.
Las Vegas Raiders vs Pittsburgh Steelers
Odds via Bovada as of Friday, September 17
- Record: Las Vegas Raiders (1-0) vs Pittsburgh Steelers (1-0)
- Start time: 1 p.m. EST
- Moneyline: Raiders (+220) vs Steelers (-270)
- Spread: Raiders +6.5 (-110) vs Steelers -6.5 (-110)
- Total: 47.0 — Over (-110), Under (-110)
- Head-to-Head: Raiders are 6-4 against the Steelers in their last 10 games.
Los Angeles Rams vs Indianapolis Colts
Odds via Bovada as of Friday, September 17
- Record: Los Angeles Rams (1-0) vs Indianapolis Colts (0-1)
- Start time: 1 p.m. EST
- Moneyline: Rams (-195) vs Colts (+165)
- Spread: Rams -3.5 (-115) vs Colts +3.5 (-105)
- Total: 48.0 — Over (-110), Under (-110)
- Head-to-Head: Rams are 3-3 against the Colts in their last six games.
NFL Odds: New England Patriots vs New York Jets
Odds via Bovada as of Friday, September 17
- Record: New England Patriots (0-1) vs New York Jets (0-1)
- Start time: 1 p.m. EST
- Moneyline: Patriots (-250) vs Jets (+210)
- Spread: Patriots -6.0 (-110) vs Jets +6.0 (-110)
- Total: 43.0 — Over (-110), Under (-110)
- Head-to-Head: Patriots are 10-0 against the Jets in their last 10 games.
New Orleans Saints vs Carolina Panthers
Odds via Bovada as of Friday, September 17
- Record: New Orleans Saints (1-0) vs Carolina Panthers (1-0)
- Start time: 1 p.m. EST
- Moneyline: Saints (-185) vs Panthers (+160)
- Spread: Saints -3.5 (-110) vs Panthers +3.5 (-110)
- Total: 44.5 — Over (-110), Under (-110)
- Head-to-Head: Saints are 8-2 against the Panthers in their last 10 games.
San Francisco 49ers vs Philadelphia Eagles
Odds via Bovada as of Friday, September 17
- Record: San Francisco 49ers (1-0) vs Philadelphia Eagles (1-0)
- Start time: 1 p.m. EST
- Moneyline: 49ers (-150) vs Eagles (+130)
- Spread: 49ers -3.0 (-105) vs Eagles +3.0 (-115)
- Total: 50.0 — Over (-105), Under (-115)
- Head-to-Head: Eagles are 7-3 against the 49ers in their last 10 games.
NFL Odds: Atlanta Falcons vs Tampa Bay Buccaneers
Odds via Bovada as of Friday, September 17
- Record: Atlanta Falcons (0-1) vs Tampa Bay Buccaneers (1-0)
- Start time: 4:05 p.m. EST
- Moneyline: Falcons (+500) vs Buccaneers (-750)
- Spread: Falcons +12.5 (-110) vs Buccaneers -12.5 (-110)
- Total: 52.0 — Over (-110), Under (-110)
- Head-to-Head: Falcons are 6-4 against the Buccaneers in their last 10 games.
Minnesota Vikings vs Arizona Cardinals
Odds via Bovada as of Friday, September 17
- Record: Minnesota Vikings (0-1) vs Arizona Cardinals (1-0)
- Start time: 4:05 p.m. EST
- Moneyline: Vikings (+165) vs Cardinals (-195)
- Spread: Vikings +3.5 (-105) vs Cardinals -3.5 (-115)
- Total: 51.0 — Over (-105), Under (-115)
- Head-to-Head: Vikings are 7-3 against the Cardinals in their last 10 games.
Dallas Cowboys vs Los Angeles Chargers
Odds via Bovada as of Friday, September 17
- Record: Dallas Cowboys (0-1) vs Los Angeles Chargers (1-0)
- Start time: 4:25 p.m. EST
- Moneyline: Cowboys (+155) vs Chargers (-180)
- Spread: Cowboys +3.5 (-115) vs Chargers -3.5 (-105)
- Total: 55.0 — Over (-115), Under (-105)
- Head-to-Head: Chargers are 4-2 against the Cowboys in their last six games.
NFL Odds: Tennessee Titans vs Seattle Seahawks
Odds via Bovada as of Friday, September 17
- Record: Tennessee Titans (0-1) vs Seattle Seahawks (1-0)
- Start time: 4:25 p.m. EST
- Moneyline: Titans (+230) vs Seahawks (-280)
- Spread: Titans +6.5 (-110) vs Seahawks -6.5 (-110)
- Total: 54.0 — Over (-110), Under (-110)
- Head-to-Head: Seahawks are 5-2 against the Titans in their last seven games.
Sunday Night Football Odds: Kansas City Chiefs vs Baltimore Ravens
Odds via Bovada as of Friday, September 17
- Record: Kansas City Chiefs (1-0) vs Baltimore Ravens (0-1)
- Start time: 4:25 p.m. EST
- Moneyline: Chiefs (-200) vs Ravens (+170)
- Spread: Chiefs -4.0 (-115) vs Ravens +4.0 (-105)
- Total: 54.5 — Over (-110), Under (-110)
- Head-to-Head: Chiefs are 6-4 against the Ravens in their last 10 games.
