NFL Odds: Lines and Spread for each of Sunday’s Week 3 Games

We are officially two weeks into the 2021 NFL season as a bundle of games are scheduled for this weekend. There are a ton of big matchups scheduled for Sunday, September 26, which means that there’s a lot to keep track of. Fortunately, this betting guide has all of the lines and spreads for each of Sunday’s games in one place, making it easy to know everything that’s important.

Here’s a look at the odds heading into each of this Sunday’s Week 3 matchups, with odds courtesy of Bovada.

NFL Odds: Arizona Cardinals vs Jacksonville Jaguars

Odds via Bovada as of Friday, September 24

  • Record: Arizona Cardinals (2-0) vs Jacksonville Jaguars (0-2)
  • Start time: 1 p.m. EST
  • Moneyline: Cardinals (-360) vs Jaguars (+280)
  • Spread: Cardinals -7.5 (-110) vs Jaguars +7.5 (-110)
  • Total: 52.0 — Over (-105), Under (-115)
  • Head-to-Head: Cardinals are 3-2 against the Jaguars in their last five games.

Atlanta Falcons vs New York Giants Odds

Odds via Bovada as of Friday, September 24

  • Record: Atlanta Falcons (0-2) vs New York Giants (0-2)
  • Start time: 1 p.m. EST
  • Moneyline: Falcons (+130) vs Giants (-150)
  • Spread: Falcons +3.0 (-125) vs Giants -3.0 (+105)
  • Total: 47.5 — Over (-110), Under (-110)
  • Head-to-Head: Falcons are 5-5 against the Giants in their last 10 games.

Chicago Bears vs Cleveland Browns Odds

Odds via Bovada as of Friday, September 24

  • Record: Chicago Bears (1-1) vs Cleveland Browns (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Bears (+270) vs Browns (-340)
  • Spread: Bears +7.5 (-110) vs Browns -7.5 (-110)
  • Total: 45.5 — Over (-105), Under (-115)
  • Head-to-Head: Bears are 4-1 against the Browns in their last five games.

NFL Odds: Cincinnati Bengals vs Pittsburgh Steelers

Odds via Bovada as of Friday, September 24

  • Record: Cincinnati Bengals (1-1) vs Pittsburgh Steelers (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Bengals (+135) vs Steelers (-160)
  • Spread: Bengals +3.0 (-105) vs Steelers -3.0 (-115)
  • Total: 43.0 — Over (-110), Under (-110)
  • Head-to-Head: Steelers are 9-1 against the Bengals in their last five games.

Indianapolis Colts vs Tennessee Titans Odds

Odds via Bovada as of Friday, September 24

  • Record: Indianapolis Colts (0-2) vs Tennessee Titans (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Colts (+210) vs Titans (-250)
  • Spread: Colts +5.5 (-110) vs Titans -5.5 (-110)
  • Total: 48.0 — Over (-105), Under (-115)
  • Head-to-Head: Colts are 6-4 against the Titans in their last 10 games.

Los Angeles Chargers vs Kansas City Chiefs Odds

Odds via Bovada as of Friday, September 24

  • Record: Los Angeles Chargers (1-1) vs Kansas City Chiefs (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Chargers (+255) vs Chiefs (-310)
  • Spread: Chargers +7.0 (-110) vs Chiefs -7.0 (-110)
  • Total: 54.5 — Over (-110), Under (-110)
  • Head-to-Head: Chiefs are 8-2 against the Chargers in their last 10 games.

NFL Odds: New Orleans Saints vs New England Patriots

Odds via Bovada as of Friday, September 24

  • Record: New Orleans Saints (1-1) vs New England Patriots (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Saints (+130) vs Patriots (-150)
  • Spread: Saints +3.0 (-120) vs Patriots -3.0 (+100)
  • Total: 42.5 — Over (-110), Under (-110)
  • Head-to-Head: Patriots are 5-2 against the Saints in their last seven games.

Baltimore Ravens vs Detroit Lions Odds

Odds via Bovada as of Friday, September 24

  • Record: Baltimore Ravens (1-1) vs Detroit Lions (0-2)
  • Start time: 1 p.m. EST
  • Moneyline: Ravens (N/A) vs Lions (N/A)
  • Spread: Ravens -7.5 (N/A) vs Lions +7.5 (N/A)
  • Total: 49.5 — Over (N/A), Under (N/A)
  • Head-to-Head: Ravens are 4-2against the Lions in their last six games.

Washington Football Team vs Buffalo Bills Odds

Odds via Bovada as of Friday, September 24

  • Record: Washington Football Team (1-1) vs Buffalo Bills (1-1)
  • Start time: 1 p.m. EST
  • Moneyline: Washington (+280) vs Bills (-360)
  • Spread: Washington +7.0 (-105) vs Bills -7.0 (-115)
  • Total: 45.5 — Over (-110), Under (-110)
  • Head-to-Head: Bills are 6-1 against Washington in their last seven games.

Miami Dolphins vs Las Vegas Raiders Odds

Odds via Bovada as of Friday, September 24

  • Record: Miami Dolphins (1-1) vs Las Vegas Raiders (2-0)
  • Start time: 4:05 p.m. EST
  • Moneyline: Dolphins (+170) vs Raiders (-200)
  • Spread: Dolphins +4.0 (-115) vs Raiders -4.0 (-105)
  • Total: 44.5 — Over (-110), Under (-110)
  • Head-to-Head: Dolphins are 8-2 against the Raiders in their last 10 games.

NFL Odds: New York Jets vs Denver Broncos

Odds via Bovada as of Friday, September 24

  • Record: New York Jets (0-2) vs Denver Broncos (2-0)
  • Start time: 4:05 p.m. EST
  • Moneyline: Jets (+435) vs Broncos (-635)
  • Spread: Jets +10.5 (-110) vs Broncos -10.5 (-110)
  • Total: 41.5 — Over (-110), Under (-110)
  • Head-to-Head: Broncos are 7-3 against the Jets in their last 10 games.

Seattle Seahawks vs Minnesota Vikings Odds

Odds via Bovada as of Friday, September 24

  • Record: Seattle Seahawks (1-1) vs Minnesota Vikings (0-2)
  • Start time: 4:25 p.m. EST
  • Moneyline: Seahawks (-125) vs Vikings (+105)
  • Spread: Seahawks -1.5 (-115) vs Vikings +1.5 (-105)
  • Total: 55.0 — Over (-110), Under (-110)
  • Head-to-Head: Seahawks are 8-2 against the Vikings in their last 10 games.

Tampa Bay Buccaneers vs Los Angeles Rams Odds

Odds via Bovada as of Friday, September 24

  • Record: Tampa Bay Buccaneers (2-0) vs Los Angeles Rams (2-0)
  • Start time: 4:25 p.m. EST
  • Moneyline: Buccaneers (-125) vs Rams (+105)
  • Spread: Buccaneers -1.5 (-110) vs Rams +1.5 (-110)
  • Total: 55.5 — Over (-110), Under (-110)
  • Head-to-Head: Rams are 7-3 against the Buccaneers in their last 10 games.

NFL Sunday Night Football Odds: Green Bay Packers vs San Francisco 49ers

Odds via Bovada as of Friday, September 24

  • Record: Green Bay Packers (1-1) vs San Francisco 49ers (2-0)
  • Start time: 8:20 p.m. EST
  • Moneyline: Packers (+140) vs 49ers (-165)
  • Spread: Packers +3.0 (-105) vs 49ers -3.0 (-115)
  • Total: 50.0 — Over (-110), Under (-110)
  • Head-to-Head: 49ers are 6-4 against the Packers in their last 10 games.

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Devon Platana
After graduating with a Masters degree in Journalism, Devon joined USGS to improve his sports writing skills. As a lifelong sports fan, one of Devon’s favorite things to do is analyze statistics across all sports.