US Open 2021 Men’s Odds: Djokovic Favored Over Medvedev, Nadal

August is an exciting month for the tennis world. The 2021 ATP Rogers Cup is currently ongoing in Toronto, Canada, however, people are already looking toward the end of the month. The 2021 men’s US Open is set to begin on Monday, August 30 at the USTA Billie Jean King National Tennis Center in New York City and conclude on Sunday, September 12. It’s the last (but certainly not least) Grand Slam tournament of the year, so you can bet that a lot of eyes will be on it.

With less than three weeks to go, Bovada has released its 2021 men’s US Open odds and is favoring Novak Djokovic to win it all at -125. Nobody really comes close to his odds, which goes to show that he is on another level over the last few years.

Djokovic isn’t a stranger when it comes to the US Open. He’s competed in the tournament 15 times in the past, winning the entire thing three times (with his most recent victory coming in 2018). Aside from that, Djokovic has made it to at least Round 4 of the US Open in every attempt since 2010, which goes to show that he’s typically a safe bet.

After winning the first three Grand Slam tournaments of the year, Djokovic has the chance to join the history books if he wins the fourth. Don Budge and Rod Laver are the only two other men to have won all four titles in a calendar year and the feat hasn’t been accomplished since 1969, which goes to show how tough it is to pull off. Considering how he always seems to up his game when the stakes are the highest, looking for Djokovic to do what he can to walk away with the US Open title.

Men’s 2021 US Open Odds

Odds via Bovada as of Wednesday, August 11

  • Novak Djokovic (-125)
  • Daniil Medvedev (+500)
  • Rafael Nadal (+650)
  • Alexander Zverev (+700)
  • Dominic Thiem (+700)
  • Stefanos Tsitsipas (+1000)
  • Roger Federer (+1200)
  • Andrey Rublev (+2500)
  • Jannik Sinner (+2500)
  • Matteo Berrettini (+2500)
  • Andy Murray (+3300)
  • Aslan Karatsev (+4000)

Complete odds list available at

Medvedev Looking to Win for the First Time

At +500 odds, Daniil Medvedev has the second-best odds to win the 2021 US Open, which would mark the first time that he’s accomplished that in his career. This will be the fifth time that the 25-year-old Russian has entered the tournament, having made the finals back in 2019. Unfortunately, things didn’t go in Medvedev’s favor as he lost a thriller in five sets to Rafael Nadal. He followed that performance up in 2020 with a semifinals appearance, however, he was swept in three sets by the eventual tournament winner, Dominic Thiem (+700).

When it comes to the current ATP tour, Medvedev has an impressive 32-9 record with two title wins. He won the Open 13 and Mallorca Open earlier this year and most recently made it to the men’s tennis semifinals of the 2021 Tokyo Olympics. Currently, Medvedev is taking part in the Rogers Cup in Toronto, so it’ll be interesting to see what kind of momentum he can build ahead of the 2021 US Open.

Rafael Nadal 2021 US Open Odds

Nobody has dominated the men’s US Open quite like Rafael Nadal (+650) has over the last 11 years. During that stretch, he’s won the event four times — by far the most in that span. Should he win the 2021 edition of the tournament, Nadal will join Pete Sampras, Jimmy Connors and Roger Federer as the only other men to win the US Open five times. That’s just not something everybody can do, which proves how clutch Nadal has been in the past.

Nadal’s last US Open victory was back in 2019, so he isn’t that far removed from it. He didn’t participate in last year’s event, so many people will be focused on how he performs. Nevertheless, Nadal was eliminated by Lloyd Harris in the third round of the 2021 Washington Open on August 5. That means that he’ll want a solid bounce-back performance at the 2021 US Open to prove any potential doubters wrong, making him a strong pick to win it all.

Devon Platana
Devon Platana

After graduating with a Masters degree in Journalism, Devon joined USGS to improve his sports writing skills. As a lifelong sports fan, one of Devon’s favorite things to do is analyze statistics across all sports.