NFL Odds: Lines and Spread for each of Sunday’s Week 4 Games

We’re officially at the fourth week into the 2021 NFL season as a bundle of games are scheduled for this weekend. There are a ton of exciting matchups going down this Sunday, October 3, which means that there’s a lot to keep track of. Fortunately, this betting guide has all of the lines and spreads for each of Sunday’s games in one place, making it easy to know everything that’s important.

Here’s a look at the odds heading into each of this Sunday’s Week 4 matchups, with odds courtesy of BetOnline.

NFL Odds: Arizona Cardinals vs Jacksonville Jaguars

Odds via BetOnline as of Friday, October 1

  • Record: Washington Football Team (1-2) vs Atlanta Falcons (1-2)
  • Start time: 1 p.m. EST
  • Moneyline: Washington (-125) vs Falcons (+105)
  • Spread: Washington -1.5 (-110) vs Falcons +1.5 (-110)
  • Total: 47.5 — Over (-110), Under (-110)
  • Head-to-Head: Falcons are 6-1 against Washington in their last seven games.

Detroit Lions vs Chicago Bears Odds

Odds via BetOnline as of Friday, October 1

  • Record: Detroit Lions (0-3) vs Chicago Bears (1-2)
  • Start time: 1 p.m. EST
  • Moneyline: Lions (+125) vs Bears (-145)
  • Spread: Lions +2.5 (+100) vs Bears -2.5 (-120)
  • Total: 41.5 — Over (-110), Under (-110)
  • Head-to-Head: Bears are 6-4 against the Lions in their last 10 games.

Tennessee Titans vs New York Jets Odds

Odds via BetOnline as of Friday, October 1

  • Record: Tennessee Titans (2-1) vs New York Jets (0-3)
  • Start time: 1 p.m. EST
  • Moneyline: Titans (-310) vs Jets (+260)
  • Spread: Titans -7 (-105) vs Jets +7 (-115)
  • Total: 44.5 — Over (-110), Under (-110)
  • Head-to-Head: Jets are 6-4 against the Titans in their last 10 games

NFL Odds: Cleveland Browns vs Minnesota Vikings

Odds via BetOnline as of Friday, October 1

  • Record: Cleveland Browns (2-1) vs Minnesota Vikings (1-2)
  • Start time: 1 p.m. EST
  • Moneyline: Browns (-133) vs Vikings (+113)
  • Spread: Browns -2.0 (-111) vs Vikings +2.0 (-109)
  • Total: 51.0 — Over (-110), Under (-110)
  • Head-to-Head: Vikings are 4-1 against the Browns in their last five games.

Indianapolis Colts vs Miami Dolphins Odds

Odds via BetOnline as of Friday, October 1

  • Record: Indianapolis Colts (0-3) vs Miami Dolphins (1-2)
  • Start time: 1 p.m. EST
  • Moneyline: Colts (+113) vs Dolphins (-133)
  • Spread: Colts +1.5 (-105) vs Dolphins -1.5 (-115)
  • Total: 42.5 — Over (-110), Under (-110)
  • Head-to-Head: Colts are 6-4 against the Dolphins in their last 10 games.

Carolina Panthers vs Dallas Cowboys Odds

Odds via BetOnline as of Friday, October 1

  • Record: Carolina Panthers (3-0) vs Dallas Cowboys (2-1)
  • Start time: 1 p.m. EST
  • Moneyline: Panthers (+175) vs Cowboys (-205)
  • Spread: Panthers +4.5 (-110) vs Cowboys -4.5 (-110)
  • Total: 52.0 — Over (-105), Under (-115)
  • Head-to-Head: Cowboys are 7-3 against the Panthers in their last 10 games.

NFL Odds: New York Giants vs New Orleans Saints

Odds via BetOnline as of Friday, October 1

  • Record: New York Giants (0-3) vs New Orleans Saints (2-1)
  • Start time: 1 p.m. EST
  • Moneyline: Giants (+270) vs Saints (-325)
  • Spread: Giants +7.5 (-115) vs Saints -7.5 (-105)
  • Total: 42.0 — Over (-110), Under (-110)
  • Head-to-Head: Saints are 6-4 against the Giants in their last 10 games.

Kansas City Chiefs vs Philadelphia Eagles Odds

Odds via BetOnline as of Friday, October 1

  • Record: Kansas City Chiefs (1-2) vs Philadelphia Eagles (1-2)
  • Start time: 1 p.m. EST
  • Moneyline: Chiefs (-315) vs Eagles (+265)
  • Spread: Chiefs -7.5 (+106) vs Eagles +7.5 (-126)
  • Total: 54.5 — Over (-108), Under (-112)
  • Head-to-Head: Chiefs are 3-3 against the Eagles in their last six games.

Houston Texans vs Buffalo Bills Odds

Odds via BetOnline as of Friday, October 1

  • Record: Houston Texans (1-2) vs Buffalo Bills (2-1)
  • Start time: 1 p.m. EST
  • Moneyline: Texans (+870) vs Bills (-1500)
  • Spread: Texans +17.0 (-107) vs Bills -17.0 (-113)
  • Total: 47.0 — Over (-110), Under (-110)
  • Head-to-Head: Texans are 6-4 against the Bills in their last 10 games.

NFL Odds: Arizona Cardinals vs Los Angeles Rams

Odds via BetOnline as of Friday, October 1

  • Record: Arizona Cardinals (3-0) vs Los Angeles Rams (3-0)
  • Start time: 4:05 p.m. EST
  • Moneyline: Cardinals (+185) vs Rams (-215)
  • Spread: Cardinals +4.5 (-115) vs Rams -4.5 (-105)
  • Total: 55.0 — Over (-105), Under (-115)
  • Head-to-Head: Rams are 9-1 against the Cardinals in their last 10 games.

Seattle Seahawks vs San Francisco 49ers Odds

Odds via BetOnline as of Friday, October 1

  • Record: Seattle Seahawks (1-2) vs San Francisco 49ers (2-1)
  • Start time: 4:05 p.m. EST
  • Moneyline: Seahawks (+128) vs 49ers (-148)
  • Spread: Seahawks +2.5 (-101) vs 49ers -2.5 (-119)
  • Total: 52.0 — Over (-110), Under (-110)
  • Head-to-Head: Seahawks are 8-2 against the 49ers in their last 10 games.

NFL Odds: Baltimore Ravens vs Denver Broncos

Odds via BetOnline as of Friday, October 1

  • Record: Baltimore Ravens (2-1) vs Denver Broncos (3-0)
  • Start time: 4:25 p.m. EST
  • Moneyline: Ravens (-116) vs Broncos (-104)
  • Spread: Ravens -1.0 (-110) vs Broncos +1.0 (-110)
  • Total: 45.0 — Over (-110), Under (-110)
  • Head-to-Head: Ravens are 5-5 against the Broncos in their last 10 games.

Pittsburgh Steelers vs Green Bay Packers Odds

Odds via BetOnline as of Friday, October 1

  • Record: Pittsburgh Steelers (1-2) vs Green Bay Packers (2-1)
  • Start time: 4:25 p.m. EST
  • Moneyline: Steelers (+240) vs Packers (-285)
  • Spread: Steelers +7.0 (-125) vs Packers -7.0 (+105)
  • Total: 45.5 — Over (-105), Under (-115)
  • Head-to-Head: Steelers are 5-2 against the Packers in their last seven games.

Sunday Night Football Tampa Bay Buccaneers vs New England Patriots Odds

Odds via BetOnline as of Friday, October 1

  • Record: Tampa Ba Buccaneers (2-1) vs New England Patriots (1-2)
  • Start time: 4:25 p.m. EST
  • Moneyline: Buccaneers (-305) vs Patriots (+255)
  • Spread: Buccaneers -7.0 (-110) vs Patriots +7.0 (-110)
  • Total: 49.0 — Over (-114), Under (-106)
  • Head-to-Head: Patriots are 4-2 against the Buccaneers in their last six games.

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Devon Platana
After graduating with a Masters degree in Journalism, Devon joined USGS to improve his sports writing skills. As a lifelong sports fan, one of Devon’s favorite things to do is analyze statistics across all sports.